ALD23: Dr Lori Alvord, Surgeon

Dr Lori Alvord

Dr Lori Arviso Alvord is an American surgeon who became the first Navajo woman to be certified in surgery in 1994. She blends traditional Navajo healing techniques with conventional Western medicine, with the aim of providing Native American people with culturally competent healthcare and accelerating the recovery process for all patients.

Alvord was born in 1958 to a Diné father and White mother on the Navajo reservation of Crownpoint, New Mexico. She initially majored in natural sciences at Dartmouth College but received low grades. Believing she wasn’t clever enough to pursue a STEM career, she switched to a double social sciences major with a minor in Native American studies, graduating in 1979.

However, a neuroanatomy course at college had ignited Alvord’s interest in neurology. She joined a neurobiology clinic as a research assistant, where colleagues encouraged her to apply to medical school. She was accepted into Stanford University Medical School and earned her MD in 1985.

Medical school is always tough, but it posed specific challenges for Alvord, whose training required her to go against some Navajo traditions. She undertook a six-year residency at Stanford University Hospital after her M.D., then began practising as a surgeon with the Indian Health Service in Gallup, New Mexico. In 1994, she earned her board certification as a surgeon – the first Diné or Navajo woman to ever do so.

During her time in Gallup, Alvord cared for her own tribal members and observed that their needs, concerns and traditions often clashed with her conventional Western medical training. She began to develop a new philosophy of surgical care that respects Native American culture. Alvord has been particularly influenced by Navajo beliefs about the importance of harmony. In the context of medicine, this involves paying attention to all aspects of a patient’s life – including their personal relationships and psychological and spiritual wellbeing – rather than trying to address physical ailments in isolation.

Alvord also incorporates Navajo songs, symbols and ceremonial rituals into her practice, recognising that these can ease stress in a way that helps accelerate healing. Respect for nature is central to Alvord’s work, too; she advocates for hospitals “where you can see trees and grass and sky and sun”.

In 1999, Alvord published a bestselling memoir about her surgical career, The Scalpel and the Silver Bear. She has held a number of prestigious academic posts in the US since the 1990s, including assistant professor of surgery and psychiatry at Dartmouth Medical School, associate faculty member for the Center for American Indian Health at Johns Hopkins School of Public Health, and associate dean of the Central Michigan University College of Medicine. In 2013, she was nominated to serve as U.S. Surgeon General.

Today, Alvord is chief of staff at Astria Health in Washington in the United States, where she continues to focus on surgical care that incorporates patients’ native culture. She has published research articles in the Journal of the American College of Surgeons, and expressed pleasure that mainstream scientific research is beginning to support  some Native philosophies and practices – from meditating to reduce stress and increase immune responses to the benefits of following a high-vegetable, low-meat diet. Her goal, she says, is to “achieve a better way to deliver health care not just for Native people, but for everyone”.

Alvord’s honours include the Wallace Sterling Lifetime Achievement Award from the Stanford Medicine Alumni Association in 2018, and recognition from the Navajo Area Health Board for her “dedication and concern for the quality of healthcare on the Navajo Nation”.

You can follow her work here:

Twitter: @lori_alvord

Further Reading

Written by Moya Crockett, with thanks to Stylist for their support.

ALD23: Dr Laura Bassi, Physicist & Philosopher

Dr Laura Bassi

Laura Bassi Veratti was an 18th century Italian physicist and philosopher who made history as the first woman in the world to have a doctorate in science. She was also the first woman to become a salaried university tutor, and possibly the first woman ever to achieve a fully-fledged scientific career.

Bassi was born in Bologna in 1711 and privately tutored from the age of five. Impressed by her intelligence, Bassi’s family doctor – who was also professor of medicine at the University of Bologna – asked to have a hand in her education, teaching her subjects including philosophy, metaphysics and logic. By the time Bassi was 20, people would visit her home to watch the brilliant young woman debate philosophy and physics with leading male academics.

The Archbishop of Bologna became Bassi’s patron, and arranged for her to publicly defend 49 philosophy theses before professors of the University of Bologna in April 1732. She was promptly awarded a doctorate in natural sciences and philosophy (the second woman to earn a doctorate in philosophy, after Elena Cornaro Piscopia in 1678, as well as the first to have a science doctorate). Bassi was also elected to the Academy of Sciences of the Institute of Bologna, making her the first female member of any Western scientific establishment.

Those weren’t the only big moments for Bassi in 1732. Later that year, she was appointed professor of natural philosophy at the University of Bologna. At 21, not only was she the university’s first female teacher, she was the first paid woman lecturer in the world.

However, while the university was keen to publicise Bassi’s appointment, it was less keen to place her on genuinely equal footing with male academics. She was blocked from teaching ordinary classes and only allowed to lecture publicly at occasional high-profile events. But Bassi had no interest in serving as a ceremonial female figurehead; she wanted to work and teach.

Unusually for the time, Bassi’s marriage helped her pursue her academic and professional ambitions. After she married fellow scientist Giuseppe Veratti in 1738, it was seen as acceptable for her to lecture from her Bologna home (a more controversial activity for a single woman). She started running eight-month courses of daily lessons that combined theoretical and experimental physics in a manner not taught at the University of Bologna.

Bassi was particularly interested in experimenting with electricity, then an exciting new discovery. Students flocked from all over Europe to learn from her. Over time, she gained a reputation as a supporter of the theories of Isaac Newton, and helped introduce Newtonian physics and natural philosophy to Italy.

She authored 28 papers, mostly on physics and hydraulics. While few of Bassi’s works survive today, her influence can be seen in her correspondence with leading scientists and philosophers of her time. Her greatest professional achievement came when she was appointed to the Chair of Experimental Physics by the Bologna Institute of Sciences in 1776. It was her final history-making moment: she was now the first woman in the world to be appointed to a chair of physics at a university.

Bassi died on 20 February 1778 aged 66, having achieved the kind of success as a scientist and academic that many others – men and women alike – could only dream of.

Further Reading

Written by Moya Crockett, with thanks to Stylist for their support.

ALD23: Clara Immerwahr, Chemist

Clara Immerwahr

Clara Helene Immerwahr was a German chemist and the first woman to be awarded a doctorate in chemistry from a German university.

Born into a Jewish family on 21 June 1870 in eastern Prussia – now part of Poland – Immerwahr initially trained as a teacher, one of few higher educational paths open to German women at the time. However, she was determined to follow in her father’s footsteps and become a chemist. She embarked on gruelling private lessons and exams to gain entry to the University of Breslau to study chemistry, where she was required to attend lectures as a guest, female university students technically being barred under Prussian law.

At university, Immerwahr became fascinated by the rapidly developing field of physical chemistry. After completing undergraduate studies, she became the first woman to undertake a PhD at the University of Breslau, receiving her doctorate in chemistry magna cum laude in 1900. She reached this milestone after eight semesters of study, two more than was required for male doctoral candidates.

Immerwahr’s research focused on solution chemistry – a central focus of chemists at the turn of the 20th century – examining issues such as solubility, ion concentration and electrochemical potential. She conducted experiments involving cadmium, copper, lead, mercury and zinc and published three papers, as well an erratum and a supplement. Her investigations didn’t break new ground in chemistry, but her presence as a female scientist in a laboratory did. When Immerwahr defended her PhD thesis on the solubility of heavy metal salts in the university’s main hall in central Breslau, many young women came to watch, intrigued by the city’s “first female doctor”.

Not long after receiving her doctorate, Immerwahr married the German chemist Fritz Haber. The rigid gender norms and societal conventions of early 20th century Prussia meant this effectively marked the end of Immerwahr’s own scientific research career, although she did try to maintain her connection to science, including by delivering public presentations on the role of chemistry and physics in the household. She is also believed to have contributed to Haber’s work, albeit with scant public recognition, including by translating some of his papers into English.

The curbing of Immerwahr’s career, along with the start of World War I and the tragic accidental deaths of two close friends (including her PhD supervisor and academic mentor), are believed to have contributed to her increasing unhappiness. She died by suicide on 2 May 1915, aged 44. The same night, her husband – sometimes referred to as the “father of chemical warfare”, due to the instrumental role he played in developing poison gases for use on the battlefield – had been at a party, celebrating the “success” of the German army’s first chlorine cloud attack against Allied troops.

There has been much debate about Immerwahr’s political beliefs, and whether her death was linked to her discomfort with her husband’s role in the German war effort. What is clear is that she was a determined and ambitious scientist whose career was curtailed by the limitations placed on women’s lives at the time. Her husband would go on to win the Nobel Prize for Chemistry in 1918.

Further Reading

Written by Moya Crockett, with thanks to Stylist for their support.

ALD23: Professor Françoise Barré-Sinoussi, Virologist

Professor Françoise Barré-Sinoussi

Françoise Barré-Sinousi is a French virologist who, alongside colleagues at the Institut Pasteur in Paris, discovered the human immunodeficiency virus (HIV) in 1983. Now Emeritus Professor at the Institut Pasteur, Barré-Sinousi has dedicated her career as a scientist and activist to helping stop the spread of AIDS.

Barré-Sinoussi grew up in Paris, where she was born in 1947. As a biomedical science student at the University of Paris, she began volunteering in Jean-Claude Chermann’s lab at the Institut Pasteur. She later returned to this lab after earning her PhD, where she researched the link between retroviruses and cancer.

In 1982, Barré-Sinoussi’s unit at the Institut Pasteur received a call from a French clinician. A mysterious and devastating new illness was driving people, predominantly gay men, into Paris hospitals. The clinician wanted to know whether a retrovirus could be behind this unknown disease. By the following year, the 35-year-old Barré-Sinoussi had detected enzyme activity that suggested – for the first time – that AIDS symptoms may be caused by a virus.

Working with Chermann, Luc Montagnier and others, Barré-Sinoussi isolated and grew a retrovirus from a biopsied swollen lymph node of a patient at risk for AIDS. This would later be named the human immunodeficiency virus. The team’s findings were confirmed in 1984, a step that allowed blood tests to be administered to diagnose and help control the spread of HIV. Their discovery also laid the groundwork for antiretroviral medications, which transformed AIDS from a death sentence into a chronic but manageable disease.

In the mid-1980s, Barré-Sinoussi travelled to Africa to see how AIDS was affecting patients across the continent. Her experiences there motivated her to work extensively in Africa and southeast Asia throughout her career, contributing to AIDS education and helping establish test and treatment centres. She co-founded the International AIDS Society (IAS) in 1988, setting up her own lab at the Institut Pasteur the same year. She has described herself as an activist as well as a scientist, saying: “There has been enormous scientific progress – and yet people are still dying of AIDS. How can I accept this? I cannot. It’s a matter of equality. Everybody has a right to live.”

In 2008, 25 years after they identified the cause of AIDS, Barré-Sinoussi and Montagnier were awarded the Nobel Prize in Physiology or Medicine. “Never before has science and medicine been so quick to discover, identify the origin and provide treatment for a new disease entity,” read the award’s announcement.

Barré-Sinoussi authored and co-authored 270 original publications over her career, furthering understanding in areas including mother-to-child HIV transmission and the adaptive immune response to viral infection. French mandatory retirement laws forced her to cease active research when she turned 68 in 2015, but she remains a tireless advocate for people with AIDS, holding senior positions in organisations including the Institut Pasteur and Inserm (the French National Institute of Health and Medical Research).

Barré-Sinoussi’s research and activism has enabled life-saving scientific advancements and shaped policy on the treatment of people living with HIV. But when reflecting on her individual contribution to the fight against AIDS, she is pragmatic. “We are all in it together, and we each make up a tiny piece of the puzzle,” she has said. “That’s all I am: a piece of the puzzle.”

She has received more than 10 major awards in addition to her Nobel Prize, and is a Grand Officer in France’s National Order of the Legion of Honour.

Further Reading

Written by Moya Crockett, with thanks to Stylist for their support.

ALD23 Books: Preventable: How a Pandemic Changed the World & How to Stop the Next One, Devi Sridhar

Preventable: How a Pandemic Changed the World & How to Stop the Next One, Devi Sridhar

Professor Devi Sridhar has risen to prominence for her vital roles in communicating science to the public and speaking truth to power. In Preventable she highlights lessons learned from outbreaks past and present in a narrative that traces the COVID-19 pandemic – including her personal experience as a scientist – and details a vision for how we can better protect ourselves from the inevitable health crises yet to come.

In gripping and heartfelt prose, Sridhar exposes the varied realities of those affected and puts you in the room with key decision-makers at crucial moments. She vibrantly conveys the twists and turns of a plot that saw deadlier variants emerge (contrary to the predictions of social-media pundits who argued it would mutate to a milder form), countries with weak health systems like Senegal and Vietnam fare better than countries like the US and the UK (which were consistently ranked as the most prepared), and the quickest development of game-changing vaccines in history (and their unfair distribution).

Combining science, politics, ethics and economics, this definitive book dissects the global structures that determine our fates, and reveals the deep-seated economic and social inequalities at their heart. It will challenge, outrage and inspire.

Order the book on Bookshop.org.uk

About the Author

Devi Sridhar is an American public health researcher who is also a Professor at the University of Edinburgh, where she holds a Personal Chair in Global Public Health. She is Founding Director of the University of Edinburgh’s Global Health Governance Programme and holds a Wellcome Trust Investigator Award.

The recipient of a Rhodes Scholarship, Devi holds an MPhil and a DPhil from Oxford University as well as a B.S. from the University of Miami’s Honors Medical Program. She was previously a Postdoctoral Research Fellow at All Souls College, Oxford University, and an Associate Professor in Global Health Politics and Fellow at Wolfson College, Oxford University. Following the West African Ebola virus epidemic, she worked with the Harvard Global Health Institute and the London School of Hygiene & Tropical Medicine to assess international responses to the outbreak and use this information to inform preparations for future pandemics.

Devi is the author of two previous books: Governing Global Health: Who Runs the World and Why? (OUP, 2017) and The Battle Against Hunger: Choice, Circumstance and the World Bank (OUP, 2008). Her work has been published in Nature, Science, The New England Journal of Medicine, The Lancet and The British Medical Journal.

You can follow Devi Sridhar’s work here:

Twitter: @devisridhar
Wikipedia: wikipedia.org/wiki/Devi_Sridhar
Instagram: @profdevisridhar

With thanks to Synergy for their support.